【Description】 A white or off –white tablet.
【Indications】 For the treatment of essential hypertension.
【Dosage and administration】
The normally suggested initial and maintenance dose is 0.15 g daily (two tablets), diet has no effect on the administration. Generally, Irbesartan 0.15 g once a day can control the 24-hour blood pressure better than 75mg(one tablet). But in some special patients, especially those over 75 years of age and patients on hemodialysis, initial dose of 75mg may be considered.
In patients fail to control blood pressure effectively with Irbesartan 0.15 g once a day, dosage may be increased to 0.30g (4 tablets) or combined with other antihypertensive drugs, additive effect has been shown especially in combination with hydrochlorothiazide diuretic.
In hypertensive patients with type 2 diabetes, the initial treatment dose should be 0.15 g once a day and can increase to 0.30g once a day to serve as a better maintenance dose for the therapy of kidney disease. This product has shown benefit to patients’ kidney in the treatment of hypertensive patients with type 2 diabetes. These results are based on the study as needed to combine this product with other anti-hypertensive drugs to achieve the blood pressure goal.
Renal insufficiency: in patients with renal insufficiency, no dosage adjustment is necessary, but in patients on hemodialysis, the use of lower initial dose (75mg) may be considered.
Intravascular volume depletion: patients with intravascular volume and / or sodium depletion should be corrected before administration.
Hepatic insufficiency: No dosage adjustment is necessary in patients with mild to moderate hepatic Insufficiency. There are no clinical experiences for patients with severe hepatic insufficiency.
【Storage】Seal and keep in cool dry place.
【Package】Blister pack, 10 tablets / plate, 2 plates / box.
【Approval No.】GYZZ H20060794